Award
National Institute of Allergy and Infectious Diseases 5U01AI169767-05
Complementing broadly neutralizing antibodies and autologous responses to restrict virus escape and durably suppress HIV-1
Recipient
University of Pennsylvania
Award Amount
$1,721,127.00
Ceiling
$1,721,127.00
Awarded
April 06, 2026
Identifier
5U01AI169767-05
Research project awarded to study HIV-1 virus escape mechanisms and antibody responses to develop durable suppression strategies using broadly neutralizing antibodies.
Description
The project focuses on HIV research, specifically on virus resistance to broadly neutralizing antibodies (bnAbs). The project involves multiple aims including mapping virus escape pathways, identifying complementary bnAbs, characterizing autologous antibody responses, and testing bnAbs in vivo.