Award

NIH Office of the Director 5K01OD031809-05

Impact of lymph node sparing on the anti-tumor response for head and neck cancer treated with radiation and immunotherapy

Recipient

Colorado State University

Award Amount

$124,227.00

Ceiling

$124,227.00

Awarded

February 19, 2026

Identifier

5K01OD031809-05

This NIH-funded project studies the effects of lymph node sparing on the immune response in head and neck cancer treated with radiation and immunotherapy, using animal models to potentially improve treatment outcomes.

Description

The project investigates how regional lymph node irradiation impacts the anti-tumor immune response in head and neck cancer (HNC) patients treated with radiation therapy (RT) and immunotherapy (IO). Using animal models, including murine and canine models, the study aims to challenge current standards of care regarding RLN irradiation.

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