Award
National Heart, Lung, and Blood Institute 5F31HL179994-02
The role of sex chromosomes in neonatal hyperoxic lung injury
Recipient
University of Pennsylvania, Philadelphia, PA, United States
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
August 06, 2026
Identifier
5F31HL179994-02
Research project funded by NHLBI to study how sex chromosomes influence neonatal lung injury and identify potential therapeutic targets using advanced genomic techniques.
Description
This project investigates the role of sex chromosome dosage and the X-linked gene Kdm6a in sex-specific outcomes using a mouse model, aiming to uncover mechanisms and therapeutic targets related to bronchopulmonary dysplasia, a chronic lung disease primarily affecting male preterm neonates.