Award
National Institute of Allergy and Infectious Diseases 5R01AI167416-05
Epigenetics of the autoantibody response in systemic lupus
Recipient
University of Texas HLTH SCIENCE CENTER
Award Amount
$710,829.00
Ceiling
$710,829.00
Awarded
August 18, 2025
Identifier
5R01AI167416-05
Research project studying epigenetic factors in systemic lupus to understand autoantibody responses and develop potential therapeutics, funded for $710,829 in 2025.
Description
The project focuses on epigenetic mechanisms in systemic lupus erythematosus (SLE), particularly involving the Tet2 epigenetic factor. The research aims to understand how environmental cues influence autoantibody responses. The project involves molecular biology, epigenetic tools, genetically modified mice, and humanized models. The project explores potential therapeutics targeting epigenetic mechanisms in autoimmune diseases.