Award
National Institute of Diabetes and Digestive and Kidney Diseases 1R56DK135533-01A1
Defining the role of antigen-specific T cell responses in NASH
Recipient
University of Colorado Denver
Award Amount
$599,541.00
Ceiling
$599,541.00
Awarded
September 09, 2024
Identifier
1R56DK135533-01A1
A research project funded by the National Institute of Diabetes and Digestive and Kidney Diseases to study T cell responses in NASH, aiming to find new therapeutic targets for chronic liver diseases.
Description
This project aims to understand the role of T cell responses in NASH to identify potential therapeutic targets. Chronic liver diseases result in significant morbidity and mortality worldwide, with liver transplantation rates climbing due to obesity and alcohol consumption. The project focuses on immune mechanisms involved in NASH, particularly T cell clonal expansion and antigen recognition, to identify novel therapeutic targets for chronic liver diseases.