Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK138907-02
Role of fibroblasts in bladder mucosal function
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$690,451.00
Ceiling
$690,451.00
Awarded
January 01, 2026
Identifier
5R01DK138907-02
This award funds a research project at the University of Pittsburgh investigating how fibroblasts in the bladder mucosa contribute to bladder function and signaling, with implications for understanding bladder diseases.
Description
Research project studying the role of fibroblasts in bladder mucosal function, focusing on the contractile properties of suburothelial fibroblasts and their impact on bladder function and afferent signaling. The study uses conditional knockout mice to explore mechanisms of bladder rugae formation and afferent nerve activation.