Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK130769-05
Sex difference in intestinal immune dysfunction, SHIV infection and reservoir
Recipient
Rutgers Biomedical and Health Sciences
Award Amount
$766,944.00
Ceiling
$766,944.00
Awarded
June 27, 2025
Identifier
5R01DK130769-05
Research project studying sex differences in immune dysfunction and viral persistence in HIV/AIDS using a rhesus macaque model, focusing on estrogen's role to develop targeted therapies.
Description
This project aims to investigate sex differences in immune activation and persistence related to HIV/AIDS, utilizing a rhesus macaque model to study immune dysregulation, viral reservoirs, and rebound mechanisms. The research focuses on the role of estrogen in modulating immune responses and viral persistence, with the goal of developing personalized therapeutic strategies.