Award
National Institute of Dental and Craniofacial Research 5R16DE034585-03
Fringe regulation of Notch signaling in osteoclasts
Recipient
Eastern Washington University
Award Amount
$120,204.00
Ceiling
$120,204.00
Awarded
July 16, 2026
Identifier
5R16DE034585-03
Research project funded by NIDCR to investigate how Fringe-catalyzed glycosylation modulates Notch signaling in osteoclasts, potentially leading to new therapies for bone loss prevention.
Description
This project studies the combinatorial effect of Fringe family glycosylation on Notch receptor activation and osteoclast formation and function, aiming to deepen understanding of Notch modulation of osteoclast formation and contribute to new bone-preserving therapies.