Award
NIH Reporter #1R01EB037010-01A1
Development of a multifunctional interventional device for biopsy and optical imaging-based phase-0 drug response measurements
Recipient
Brigham and Women's Hospital, Boston, MA
Award Amount
$749,901.00
Ceiling
$749,901.00
Awarded
April 28, 2026
Identifier
1R01EB037010-01A1
The award funds the development of a novel interventional device to rapidly and safely measure drug responses in patients using biopsy and optical imaging, aiming to improve drug development efficiency and personalized treatment.
Description
This project aims to develop a minimally invasive, safe, and effective interventional device (IDRA) for biopsy-based Phase-0 drug response measurements. The device will enable safe, outpatient procedures for sampling and analyzing drug effects in tumors, facilitating early drug development and personalized medicine. The project includes validation in preclinical models and integration of optical imaging for real-time visualization of drug effects.