Award

NIH Reporter #1R01EB037010-01A1

Development of a multifunctional interventional device for biopsy and optical imaging-based phase-0 drug response measurements

Recipient

Brigham and Women's Hospital, Boston, MA

Award Amount

$749,901.00

Ceiling

$749,901.00

Awarded

April 28, 2026

Identifier

1R01EB037010-01A1

The award funds the development of a novel interventional device to rapidly and safely measure drug responses in patients using biopsy and optical imaging, aiming to improve drug development efficiency and personalized treatment.

Description

This project aims to develop a minimally invasive, safe, and effective interventional device (IDRA) for biopsy-based Phase-0 drug response measurements. The device will enable safe, outpatient procedures for sampling and analyzing drug effects in tumors, facilitating early drug development and personalized medicine. The project includes validation in preclinical models and integration of optical imaging for real-time visualization of drug effects.

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