Award
National Institute of Neurological Disorders and Stroke 5R01NS124123-05
TNFR2 sex differences and EAE
Recipient
George Washington University
Award Amount
$403,750.00
Ceiling
$403,750.00
Awarded
December 17, 2025
Identifier
5R01NS124123-05
Research project funded by the National Institute of Neurological Disorders and Stroke to study sex-specific effects of TNFR2 signaling in EAE and develop targeted therapies for multiple sclerosis.
Description
This project investigates sex bias in Experimental Autoimmune Encephalomyelitis (EAE) and the therapeutic potential of a novel TNFR2 agonist. It aims to understand mechanisms that reduce neurological burden and support remyelination and regeneration in males and females.