Award
National Institute of Allergy and Infectious Diseases 1R01AI177367-01A1
Optimizing anti-microbial immunity by targeting Sts-1
Recipient
State University of New York at Stony Brook
Award Amount
$3,125,627.00
Ceiling
$3,125,627.00
Awarded
July 23, 2025
Identifier
1R01AI177367-01A1
NIH awarded a project to develop therapeutic strategies targeting Sts-1 to enhance anti-microbial immunity, including inhibitor optimization and efficacy testing.
Description
This NIH project aims to develop new therapeutic strategies to enhance anti-microbial immune responses by targeting the Sts-1 phosphatase. The project involves lead optimization of inhibitors, elucidation of intracellular activities, and in vivo efficacy testing. The award is part of the NIH's efforts to combat infectious diseases and antimicrobial resistance.