Award
NIH Reporter #1ZIABC011378-15
Studies of amplification in rhabdomyosarcoma
Recipient
DIVISION OF BASIC SCIENCES - NCI, UNITED STATES
Award Amount
$673,030.00
Ceiling
$673,030.00
Awarded
October 04, 2023
Identifier
1ZIABC011378-15
The award supports research on gene amplification in fusion-positive rhabdomyosarcoma, specifically studying the transcriptional regulation of MIR17HG and its role in oncogenic transformation.
Description
This project investigates the transcriptional regulation of MIR17HG in fusion-positive rhabdomyosarcoma, focusing on a distal P3F-bound DNA element critical for its expression and oncogenic transformation phenotypes.