Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R01HD028088-31
Genetic Analysis of Hirschsprung Disease - Renewal
Recipient
New York University School of Medicine
Award Amount
$633,354.00
Ceiling
$633,354.00
Awarded
August 06, 2024
Identifier
5R01HD028088-31
Award for genetic research on Hirschsprung disease to improve risk prediction and understand genetic mechanisms for therapeutic development.
Description
Hirschsprung disease (HSCR), or congenital aganglionosis, results from defects in enteric neural crest cell precursor (ENCC) development in a sex-biased manner. The project aims to improve risk prediction, understand mechanisms at genetic and cellular levels, and identify genetic steps for therapeutics.