Award
NIH Reporter #1U01AI192609-01
The oral environment in food allergy development (ONEIDA)
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY, UNITED STATES
Award Amount
$6,732,986.00
Ceiling
$6,732,986.00
Awarded
July 23, 2025
Identifier
1U01AI192609-01
A research project funded by NIAID to investigate early-life oral immune responses and microbial factors in food allergy development in a large birth cohort, aiming to inform prevention and diagnostic strategies.
Description
This project will study a multi-center birth cohort of 2,500 children recruited from 12 US sites to explore the development of food allergy during the first three years of life, focusing on oral immune development, microbial communities, and metabolites. The study aims to identify predictors and mechanisms of food allergy onset, with potential to inform prevention strategies and biomarkers using non-invasive saliva samples.