Award

National Institute of Mental Health 1R21MH141228-01A1

Examining the Interplay of Clinical Symptoms, Neurocognition, Functioning, and Stressful Events in Individuals at Clinical High Risk for Developing Psychosis: A Network Analysis Approach

Recipient

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH

Award Amount

$460,625.00

Ceiling

$460,625.00

Awarded

July 27, 2026

Identifier

1R21MH141228-01A1

A research project applying network theory to model factors contributing to psychosis risk, aiming to identify treatment targets and progression pathways to prevent schizophrenia in high-risk youth.

Description

This project will create the first data-driven guide to the most effective treatment targets by mapping interactions of clinical symptoms, neurocognitive deficits, social functioning, and environmental stressors in individuals at clinical high risk for developing psychosis. The research aims to accelerate the development of personalized interventions to prevent schizophrenia onset in vulnerable youth.

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