# NIH Reporter #11579903

Beyond Lysis: Deciphering the Role of Perforin-Mediated Ferroptosis in Anti-Tumor Immunity

**Recipient:** University of Michigan at Ann Arbor

**Award Amount:** $248,999.00
**Ceiling:** $248,999.00

**Awarded:** September 07, 2026

**Identifier:** 11579903

NIH grant awarded to University of Michigan to study perforin-mediated ferroptosis in tumor cells to enhance anti-tumor immunity and develop new immunotherapies.

### Description

This NIH grant focuses on understanding the role of perforin in inducing ferroptosis in tumor cells, aiming to develop novel immunotherapies. The project involves multidisciplinary approaches and extensive training in mass spectrometry, flow cytometry, bioinformatics, and CAR-T technology.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11579903)