Award
National Institute on Drug Abuse 1R01DA065785-01
Clinical Pharmacology of Oral Nicotine Pouches
Recipient
University of California, San Francisco
Award Amount
$819,998.00
Ceiling
$819,998.00
Awarded
July 17, 2026
Identifier
1R01DA065785-01
This award funds a study comparing the pharmacology and cardiovascular effects of oral nicotine pouches with cigarette smoking and vaping to inform public health policies on nicotine product regulation.
Description
A clinical pharmacology study to compare nicotine exposure, subjective effects, and cardiovascular effects from multiple administrations of oral nicotine pouches (3 mg and 6 mg nicotine) to a placebo ONP (0 mg) and cigarette smoking or e-cigarette use. The study aims to inform public health and regulatory policy regarding the rapid uptake of oral nicotine pouches.