Award
NIH Reporter #11382708
Topologically complex DNA substrates to aid structure determination of the human topoisomerase IIa
Recipient
Not Specified
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
July 08, 2026
Identifier
11382708
Award for research on DNA topoisomerase IIa structure determination to aid therapeutic development, funded by the National Cancer Institute.
Description
This project involves structural and biophysical studies of DNA topoisomerase IIa, including cryo-EM imaging and analysis of enzyme-DNA interactions, with a focus on understanding drug interference mechanisms for therapeutic development.