Award
National Institute of Neurological Disorders and Stroke 5R01NS122724-04
Mechanisms and Therapeutic Targeting of Chronic Neuroinflammation in Traumatic Brain Injury
Recipient
Augusta University
Award Amount
$346,499.00
Ceiling
$346,499.00
Awarded
March 10, 2025
Identifier
5R01NS122724-04
Award for research on chronic neuroinflammation mechanisms and therapeutic targeting in traumatic brain injury, including testing senolytic drugs for treatment.
Description
This project aims to elucidate mechanisms of chronic neuroinflammation after traumatic brain injury (TBI) and test therapeutic interventions targeting these mechanisms, including senolytic drugs to ablate senescent A1 astrocytes and microglia. The research is highly innovative and could provide long-term treatment options for TBI patients.