Award

National Institute on Drug Abuse 5R01DA054347-04

Cannabis Modulation of Outcomes Related to Opioid Use Disorder: Opioid Withdrawal, Opioid Abuse Potential and Opioid Safety

Recipient

University of Kentucky, Lexington, KY, United States

Award Amount

$677,778.00

Ceiling

$677,778.00

Awarded

January 26, 2026

Identifier

5R01DA054347-04

The award funds research to study the effects of cannabis on opioid use disorder outcomes, including withdrawal, abuse potential, and safety, through controlled inpatient studies.

Description

This project investigates the effects of cannabis on opioid withdrawal, abuse potential, and safety in individuals with opioid use disorder, using inpatient, randomized, double-blind, placebo-controlled studies. Two inpatient studies will be conducted to explore how acute and repeated cannabis administration impacts opioid abuse potential, withdrawal severity, and safety/physiological effects in individuals with opioid use disorder.

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