Award
National Institute of Neurological Disorders and Stroke 1K99NS142560-01A1
Striatal Mu Opioid Receptor Containing Neurons in L-DOPA induced dyskinesia
Recipient
University of Florida, Gainesville, FL
Award Amount
$114,102.00
Ceiling
$114,102.00
Awarded
May 05, 2026
Identifier
1K99NS142560-01A1
Research project funded by NIH to study the role of mu opioid receptor containing neurons in L-DOPA induced dyskinesia using advanced neuroscience techniques in a mouse model.
Description
This project investigates the mechanism by which OPRM1 single nucleotide polymorphism affects neural activity and L-DOPA induced dyskinesia (LID), and dissects the effects of MOR+ striatal neuron subgroups on LID, potentially allowing development of novel therapeutic pathways for LID.