Award
National Institute of Dental and Craniofacial Research 1R21DE033537-01A1
Role of a novel G protein-coupled mast cell receptor-mediated pathways in periodontal disease
Recipient
University of Pennsylvania
Award Amount
$446,875.00
Ceiling
$446,875.00
Awarded
September 04, 2024
Identifier
1R21DE033537-01A1
NIH grant awarded to study the role of a novel mast cell receptor in periodontal disease using humanized mouse models to develop therapeutic interventions.
Description
This NIH research grant opportunity focuses on periodontitis, a chronic inflammatory disease leading to destruction of tooth-supporting structures. The project aims to develop humanized mouse models to study the role of the receptor MRGPRX2 in mast cells and target signaling pathways for therapeutic intervention.