Award
National Center for Complementary and Integrative Health 1R21AT013586-01
Brain mechanisms of reinforced placebo pill responses in chronic pain.
Recipient
Northwestern University
Award Amount
$401,725.00
Ceiling
$401,725.00
Awarded
August 07, 2026
Identifier
1R21AT013586-01
A research project funded to study brain mechanisms behind placebo pill responses in chronic back pain patients, including effects of naloxone and influences of sex, race, and socioeconomic factors.
Description
This project aims to identify brain circuits and molecular mechanisms underlying placebo pill responses in chronic back pain patients. The study involves a randomized, partially blinded trial with reinforcement cues to enhance placebo responses, and investigates the effects of naloxone on brain activity related to placebo responses.