Award
National Cancer Institute 5R21CA282857-02
Discovery and anti-tumor activity of the first antagonists targeting human Sonic Hedgehog autoprocessing
Recipient
Not specified
Award Amount
$219,881.00
Ceiling
$219,881.00
Awarded
January 01, 2025
Identifier
5R21CA282857-02
NIH-funded research project to discover and test small molecule antagonists for Sonic Hedgehog autoprocessing as targeted cancer therapy, awarded by the National Cancer Institute with a total funding of $219,881 for FY 2025.
Description
This NIH-funded project aims to discover and evaluate small molecule antagonists targeting human Sonic Hedgehog autoprocessing, with potential applications in cancer therapeutics, specifically for multiple myeloma and colon cancer. The project includes high throughput screening, preclinical testing, and collaboration with NCATS.