# NIH Reporter #5R35CA263922-05

Interaction between Nuclear Epigenetic and Metabolic Pathways in Cancer

**Recipient:** University of Pennsylvania

**Award Amount:** $975,000.00
**Ceiling:** $975,000.00

**Awarded:** July 27, 2026

**Identifier:** 5R35CA263922-05

The University of Pennsylvania will study how epigenetic and metabolic pathways interact in cancer, with the aim of identifying mechanisms that may inform future treatments.

### Description

Research project investigating the interaction between epigenetic regulation and nuclear metabolism in cancer, including enhancers, p53 function, nuclear speckles, and the nuclear metabolic enzyme ACSS2.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11403879)