Award
National Institute of Dental and Craniofacial Research 5R35DE031926-05
Signaling control and cellular basis of craniofacial morphogenesis and congenital disease
Recipient
University of California, San Francisco
Award Amount
$1,032,684.00
Ceiling
$1,032,684.00
Awarded
April 20, 2026
Identifier
5R35DE031926-05
The award supports research to understand cellular and molecular mechanisms underlying craniofacial development and congenital anomalies, potentially leading to new therapeutic approaches.
Description
This project aims to advance understanding of craniofacial development and congenital anomalies through innovative cellular and molecular research, with potential therapeutic implications. It focuses on the cellular behaviors during craniofacial morphogenesis in mouse embryos and human models, using CRISPR/Cas9 technology to study mesenchymal cell movement, epithelial tissue fusion, and regulators of craniofacial morphogenesis.