Award

NIH Reporter #1R21AG098225-01

Lysosomal dysfunction as a risk factor in Alzheimer disease

Recipient

University of Illinois at Chicago

Award Amount

$240,495.00

Ceiling

$240,495.00

Awarded

September 18, 2026

Identifier

1R21AG098225-01

NIH-funded research examining whether reduced activity of the lysosomal enzyme GALC is associated with amyloid accumulation and Alzheimer disease progression.

Description

Pilot project conducting biochemical and genomic analyses in human Alzheimer disease cases and an Alzheimer disease animal model with partially reduced GALC activity to investigate the relationship between lysosomal dysfunction and disease progression.

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