Award
National Institute of Allergy and Infectious Diseases 5K08AI170918-02
Cellular mechanisms of macrophage activation syndrome
Recipient
University of Washington, Seattle, WA, United States
Award Amount
$187,692.00
Ceiling
$187,692.00
Awarded
June 02, 2026
Identifier
5K08AI170918-02
This award supports research to understand the cellular and molecular mechanisms of macrophage activation syndrome, aiming to improve diagnosis and treatment by studying immune responses and interactions at the cellular level.
Description
The project focuses on investigating the cellular mechanisms of macrophage activation syndrome (MAS), including the roles of cytokines, innate immune sensors, and monocyte responses, with aims to define cellular and molecular landscapes, test hypotheses about gene expression and signaling pathways, and elucidate monocyte-T cell interactions.