Award
National Institute of Allergy and Infectious Diseases 5R01AI170193-05
The novel role of beta3 integrin in regulating alloimmunity
Recipient
Brigham and Women's Hospital, Boston, MA, United States
Award Amount
$749,489.00
Ceiling
$749,489.00
Awarded
January 21, 2026
Identifier
5R01AI170193-05
Research project funded by NIAID to study the role of β3 integrin in heart transplant rejection and develop nanoparticle-based therapies to improve graft acceptance.
Description
This project aims to investigate the mechanisms by which β3 integrin regulates immune responses in heart transplantation, with a focus on developing novel therapeutic strategies using nanoparticle delivery systems to improve graft survival.