Award
National Heart, Lung, and Blood Institute 5R01HL160980-05
Dietary interventions to modulate heart health in offspring born to diabetic mothers and the subsequent generation
Recipient
Sanford Research/USD, Sioux Falls, SD, United States
Award Amount
$415,000.00
Ceiling
$415,000.00
Awarded
February 26, 2026
Identifier
5R01HL160980-05
A research grant awarded to study dietary interventions to reduce heart disease risk in offspring of diabetic mothers by targeting oxidative DNA damage and dietary fat intake during pregnancy.
Description
This project aims to develop interventions to improve heart health in offspring of diabetic mothers, focusing on oxidative DNA damage and dietary strategies during pregnancy and family planning. It investigates if oxidative DNA damage contributes to programmed heart disease in offspring, assesses if limiting dietary fat during pregnancy reduces risks, and evaluates if antioxidant Coenzyme Q10 (CoQ10) prevents programmed heart disease.