Award
National Institute of Allergy and Infectious Diseases 5R01AI147319-06
Capturing spatial patterns of new M. tuberculosis infection in Kampala, Uganda
Recipient
Case Western Reserve University, Cleveland, OH, United States
Award Amount
$793,932.00
Ceiling
$793,932.00
Awarded
July 22, 2024
Identifier
5R01AI147319-06
A research project funded by NIAID to develop biomarkers and spatial analysis methods to detect new tuberculosis infections in Kampala, Uganda, to improve targeted prevention efforts.
Description
This project aims to develop and validate serum/plasma biomarker signatures to identify new M. tuberculosis infections in high transmission areas, particularly in Kampala, Uganda. The research involves testing a host protein signature, identifying infection hotspots using GPS technology, and validating biomarkers in community settings. The goal is to enable targeted preventive therapy to reduce TB transmission.