Award
NIH Reporter #11340378
Heterosynaptic mechanisms driving elevated synaptic inhibition and plasticity impairments following ischemia.
Recipient
University of Colorado Denver
Award Amount
$473,860.00
Ceiling
$473,860.00
Awarded
May 07, 2026
Identifier
11340378
NIH grant awarded to University of Colorado Denver to study synaptic inhibition and plasticity impairments after ischemia, aiming to find therapeutic targets for cognitive improvement post-cardiac arrest.
Description
The project focuses on investigating synaptic mechanisms following ischemia using electrophysiology, imaging, and biochemistry in a rodent model. The long-term goal is to identify therapeutic targets to improve cognitive outcomes after cardiac arrest. The project involves pharmacological, genetic, and optogenetic manipulations.