Award
National Institute of Allergy and Infectious Diseases 5R01AI175437-03
A Novel, Multi-compartment Intravaginal Ring for Prevention of Genital Herpes and Unintended Pregnancy
Recipient
Oak Crest Institute of Science
Award Amount
$815,431.00
Ceiling
$815,431.00
Awarded
July 14, 2026
Identifier
5R01AI175437-03
This NIH-funded project aims to develop a multipurpose intravaginal ring that prevents genital herpes, HPV, HIV, and unintended pregnancy by delivering antiviral peptides and sperm inhibitors in a controlled manner.
Description
Development of a next-generation multipurpose intravaginal ring (IVR) with antiviral peptides active against HSV, HPV, and HIV; small-molecule inhibitors of sperm function; and a platform for long-acting, controlled delivery of these agents. The research includes evaluating antiviral peptides and sperm inhibitors, formulating IVRs, and assessing pharmacokinetics and safety in animal models.